There are two kinds of predictions in my mind:
1. The obvious ones, like Kate Middleton will have a baby, a new Mac will come out, mobile will be huge, etc.
2. The real ones, which somehow could be used to your advantage. If you had these, why would you tell anyone else? To be right? What's that worth unless you're Nate Silver?
I'd rather just bet on or do the unpredictable thing.